[4] Bayer Leverkusen 1-0 Mainz [5] 2021-09-25 13:30
Stadium: BayArena Round: 6
Referee: Bastian Dankert Home Manager: Gerardo Seoane Away Manager: Bo Svensson
Head to Head
| Germany Bundesliga I | 2021/02/13 14:30 | Bayer Leverkusen v Mainz | D | 2-2 |
| Germany Bundesliga I | 2020/10/17 13:30 | Mainz v Bayer Leverkusen | W | 0-1 |
| Germany Bundesliga I | 2020/06/27 13:30 | Bayer Leverkusen v Mainz | W | 1-0 |
| Germany Bundesliga I | 2019/12/21 14:30 | Mainz v Bayer Leverkusen | W | 0-1 |
| Germany Bundesliga I | 2019/02/08 19:30 | Mainz v Bayer Leverkusen | W | 1-5 |
| Germany Bundesliga I | 2018/09/23 13:30 | Bayer Leverkusen v Mainz | W | 1-0 |
| Germany Bundesliga I | 2018/01/28 14:30 | Bayer Leverkusen v Mainz | W | 2-0 |
| Germany Bundesliga I | 2017/09/09 13:30 | Mainz v Bayer Leverkusen | L | 3-1 |
Home History
| Germany Bundesliga I | 2021/09/19 13:30 | VfB Stuttgart v Bayer Leverkusen | W | 1-3 |
| UEFA Europa League | 2021/09/16 16:45 | Bayer Leverkusen v Ferencvarosi TC | W | 2-1 |
| Germany Bundesliga I | 2021/09/11 13:30 | Bayer Leverkusen v Borussia Dortmund | L | 3-4 |
| Germany Bundesliga I | 2021/08/28 13:30 | Augsburg v Bayer Leverkusen | W | 1-4 |
| Germany Bundesliga I | 2021/08/21 16:30 | Bayer Leverkusen v Borussia M'gladbach | W | 4-0 |
| Germany Bundesliga I | 2021/08/14 13:30 | Union Berlin v Bayer Leverkusen | D | 1-1 |
| Germany DFB Pokal | 2021/08/07 13:30 | FC Lok Leipzig v Bayer Leverkusen | W | 0-3 |
| Club Friendly List | 2021/07/23 12:00 | Bayer Leverkusen v SC Freiburg | D | 0-0 |
Away History
| Germany Bundesliga I | 2021/09/18 13:30 | Mainz v SC Freiburg | D | 0-0 |
| Germany Bundesliga I | 2021/09/11 13:30 | TSG Hoffenheim v Mainz | W | 0-2 |
| Europe Friendlies | 2021/09/02 11:00 | Mainz v Karlsruhe | D | 0-0 |
| Germany Bundesliga I | 2021/08/28 13:30 | Mainz v Greuther Furth | W | 3-0 |
| Germany Bundesliga I | 2021/08/21 13:30 | Bochum v Mainz | L | 2-0 |
| Germany Bundesliga I | 2021/08/15 13:30 | Mainz v RB Leipzig | W | 1-0 |
| Germany DFB Pokal | 2021/08/08 13:30 | Elversberg v Mainz | W | 9-10 |
| Club Friendly List | 2021/07/31 15:30 | Mainz v Genoa | W | 3-2 |