[6] Man Utd 1-1 Southampton [10] 2022-02-12 12:30
Stadium: Old Trafford Round: 25
Referee: Stuart Attwell Home Manager: Ralf Rangnick Away Manager: Ralph Hasenhuttl
Head to Head
| England Premier League | 2021/08/22 13:00 | Southampton v Man Utd | D | 1-1 |
| England Premier League | 2021/02/02 20:15 | Man Utd v Southampton | W | 9-0 |
| England Premier League | 2020/11/29 14:00 | Southampton v Man Utd | W | 2-3 |
| England Premier League | 2020/07/13 19:00 | Man Utd v Southampton | D | 2-2 |
| England Premier League | 2019/08/31 11:30 | Southampton v Man Utd | D | 1-1 |
| England Premier League | 2019/03/02 15:00 | Man Utd v Southampton | W | 3-2 |
| England Premier League | 2018/12/01 17:30 | Southampton v Man Utd | D | 2-2 |
| England Premier League | 2017/12/30 17:30 | Man Utd v Southampton | D | 0-0 |
Home History
| England Premier League | 2022/02/08 20:00 | Burnley v Man Utd | D | 1-1 |
| England FA Cup | 2022/02/04 20:00 | Man Utd v Middlesbrough | L | 8-9 |
| England Premier League | 2022/01/22 15:00 | Man Utd v West Ham | W | 1-0 |
| England Premier League | 2022/01/19 20:00 | Brentford v Man Utd | W | 1-3 |
| England Premier League | 2022/01/15 17:30 | Aston Villa v Man Utd | D | 2-2 |
| England FA Cup | 2022/01/10 19:55 | Man Utd v Aston Villa | W | 1-0 |
| England Premier League | 2022/01/03 17:30 | Man Utd v Wolverhampton | L | 0-1 |
| England Premier League | 2021/12/30 20:15 | Man Utd v Burnley | W | 3-1 |
Away History
| England Premier League | 2022/02/09 19:45 | Tottenham v Southampton | W | 2-3 |
| England FA Cup | 2022/02/05 15:00 | Southampton v Coventry | W | 2-1 |
| England Premier League | 2022/01/22 17:30 | Southampton v Man City | D | 1-1 |
| England Premier League | 2022/01/15 15:00 | Wolverhampton v Southampton | L | 3-1 |
| England Premier League | 2022/01/11 19:45 | Southampton v Brentford | W | 4-1 |
| England FA Cup | 2022/01/08 17:30 | Swansea v Southampton | W | 2-3 |
| England Premier League | 2021/12/28 15:00 | Southampton v Tottenham | D | 1-1 |
| England Premier League | 2021/12/26 15:00 | West Ham v Southampton | W | 2-3 |