[42] Taylor Fritz 6-7,7-5,3-6 John Isner [35] 2021-07-31 23:00
Stadium: Stadium Court Round: 28 Ground: Hardcourt outdoor
Head to Head
| All American Team Cup | 2020/07/03 22:00 | John Isner v Taylor Fritz | 6-3,6-4 |
| ATP Acapulco | 2020/02/29 00:05 | Taylor Fritz v John Isner | 2-6,7-5,6-3 |
| ATP Auckland | 2019/01/08 23:00 | John Isner v Taylor Fritz | 6-7,6-7 |
| Wimbledon | 2017/07/04 16:35 | Taylor Fritz v John Isner | 4-6,6-7,3-6 |
Home History
| ATP Atlanta | 2021/07/30 18:10 | Taylor Fritz v Reilly Opelka | 7-6,6-7,7-6 |
| ATP Atlanta | 2021/07/28 17:30 | Taylor Fritz v Steve Johnson | 6-7,6-4,6-1 |
| ATP Atlanta | 2021/07/27 17:30 | Taylor Fritz v Evgeny Donskoy | 6-3,6-4 |
| ATP Los Cabos | 2021/07/24 01:30 | Cameron Norrie v Taylor Fritz | 6-3,6-1 |
| ATP Los Cabos | 2021/07/23 00:40 | Taylor Fritz v Steve Johnson | 6-4,6-4 |
| ATP Los Cabos | 2021/07/22 04:50 | Taylor Fritz v Illya Marchenko | 6-1,6-7,7-5 |
| Wimbledon | 2021/07/03 13:10 | Taylor Fritz v Alexander Zverev | 7-6,4-6,3-6,6-7 |
| Wimbledon | 2021/07/01 13:45 | Taylor Fritz v Steve Johnson | 6-4,7-6,4-6,6-7,6-4 |
Away History
| ATP Atlanta | 2021/07/31 00:00 | John Isner v Christopher O'Connell | 7-6,6-7,6-4 |
| ATP Atlanta | 2021/07/29 23:00 | John Isner v Jack Sock | 7-6,6-4 |
| ATP Atlanta | 2021/07/27 19:00 | John Isner v Jeffrey John Wolf | 6-4,6-7,6-4 |
| ATP Los Cabos | 2021/07/24 03:00 | Brandon Nakashima v John Isner | 7-5,6-4 |
| ATP Los Cabos | 2021/07/23 02:30 | Alex Bolt v John Isner | 3-6,4-6 |
| ATP Los Cabos | 2021/07/22 02:15 | Evgeny Donskoy v John Isner | 5-7,6-3,6-7 |
| Wimbledon | 2021/06/30 10:00 | Yoshihito Nishioka v John Isner | 7-6,2-6,6-3,6-7,6-4 |
| French Open | 2021/06/04 19:00 | Stefanos Tsitsipas v John Isner | 5-7,6-3,7-6,6-1 |