| Panama Liga Prom | 2021/04/14 23:00 | Panama City FC v Sporting San Miguelito Reserves | L | 2-0 |
| Panama Liga Prom | 2021/10/09 21:00 | Potros Del Este Reserves v Sporting San Miguelito Reserves | D | 0-0 |
| Panama Liga Prom | 2021/10/02 22:00 | Plaza Amador Reserves v Sporting San Miguelito Reserves | W | 0-1 |
| Panama Liga Prom | 2021/09/26 14:00 | Sporting San Miguelito Reserves v San Martin FC | D | 1-1 |
| Panama Liga Prom | 2021/09/17 23:00 | Sporting San Miguelito Reserves v Tauro FC Reserves | L | 1-2 |
| Panama Liga Prom | 2021/09/09 21:00 | Alianza FC Reserves v Sporting San Miguelito Reserves | W | 2-3 |
| Panama Liga Prom | 2021/09/03 23:00 | Sporting San Miguelito Reserves v Champions FC Academy | D | 0-0 |
| Panama Liga Prom | 2021/08/27 23:00 | Sporting San Miguelito Reserves v Colon C-3 | D | 1-1 |
| Panama Liga Prom | 2021/08/21 23:00 | Sporting San Miguelito Reserves v UMECIT | L | 0-1 |
| Panama Liga Prom | 2021/10/03 23:00 | Panama City FC v CD Arabe Unido Reserves | L | 0-2 |
| Panama Liga Prom | 2021/09/25 21:00 | Colon C-3 v Panama City FC | L | 2-0 |
| Panama Liga Prom | 2021/09/19 21:00 | Champions FC Academy v Panama City FC | L | 1-0 |
| Panama Liga Prom | 2021/09/13 00:30 | Panama City FC v UMECIT | W | 2-1 |
| Panama Liga Prom | 2021/09/04 14:00 | Panama City FC v San Martin FC | D | 1-1 |
| Panama Liga Prom | 2021/08/30 00:00 | Panama City FC v Potros Del Este Reserves | L | 1-5 |
| Panama Liga Prom | 2021/08/21 23:00 | Panama City FC v Tauro FC Reserves | L | 1-2 |
| Panama Liga Prom | 2021/08/14 23:00 | Plaza Amador Reserves v Panama City FC | L | 2-0 |