| Panama Liga Prom | 2021/08/27 20:00 | CD Universitario Reserves v Union Cocle | W | 0-2 |
| Panama Liga Prom | 2021/11/06 00:00 | Mario Mendez FC v Union Cocle | L | 3-0 |
| Panama Liga Prom | 2021/10/31 20:00 | Union Cocle v Veraguas CD Reserves | L | 0-4 |
| Panama Liga Prom | 2021/10/20 23:01 | Herrera FC Reserves v Union Cocle | L | 3-0 |
| Panama Liga Prom | 2021/10/17 00:00 | San Francisco Reserves v Union Cocle | L | 3-0 |
| Panama Liga Prom | 2021/10/02 22:00 | CA Independiente de la Chorrera Reserves v Union Cocle | L | 4-0 |
| Panama Liga Prom | 2021/09/25 20:00 | Union Cocle v SD Panama Oeste | L | 0-2 |
| Panama Liga Prom | 2021/09/17 20:00 | Union Cocle v SD Atletico Nacional | L | 1-6 |
| Panama Liga Prom | 2021/09/09 20:00 | Udelas FC v Union Cocle | L | 2-0 |
| Panama Liga Prom | 2021/11/06 22:00 | Atletico Chiriqui B v CD Universitario Reserves | L | 3-1 |
| Panama Liga Prom | 2021/10/29 20:00 | CD Universitario Reserves v Mario Mendez FC | L | 0-1 |
| Panama Liga Prom | 2021/10/21 21:00 | Veraguas CD Reserves v CD Universitario Reserves | L | 2-0 |
| Panama Liga Prom | 2021/10/08 20:00 | CD Universitario Reserves v CA Independiente de la Chorrera Reserves | W | 1-0 |
| Panama Liga Prom | 2021/10/02 22:00 | Aguilas de la U v CD Universitario Reserves | L | 3-2 |
| Panama Liga Prom | 2021/09/24 20:00 | CD Universitario Reserves v San Francisco Reserves | L | 2-4 |
| Panama Liga Prom | 2021/09/19 22:00 | SD Panama Oeste v CD Universitario Reserves | L | 4-0 |
| Panama Liga Prom | 2021/09/11 22:00 | SD Atletico Nacional v CD Universitario Reserves | L | 3-2 |