| Panama Liga Prom | 2021/08/30 00:00 | Panama City FC v Potros Del Este Reserves | W | 1-5 |
| Panama Liga Prom | 2021/05/02 23:00 | Panama City FC v Potros Del Este Reserves | L | 1-0 |
| Panama Liga Prom | 2021/03/09 22:00 | Potros Del Este Reserves v Panama City FC | W | 2-0 |
| Panama Liga Prom | 2021/11/07 00:00 | Plaza Amador Reserves v Potros Del Este Reserves | L | 5-1 |
| Panama Liga Prom | 2021/10/30 23:58 | Potros Del Este Reserves v Alianza FC Reserves | L | 1-2 |
| Panama Liga Prom | 2021/10/21 22:00 | San Martin FC v Potros Del Este Reserves | W | 1-2 |
| Panama Liga Prom | 2021/10/15 20:00 | UMECIT v Potros Del Este Reserves | W | 1-3 |
| Panama Liga Prom | 2021/10/09 21:00 | Potros Del Este Reserves v Sporting San Miguelito Reserves | D | 0-0 |
| Panama Liga Prom | 2021/10/03 21:00 | Colon C-3 v Potros Del Este Reserves | W | 2-3 |
| Panama Liga Prom | 2021/09/25 22:00 | Potros Del Este Reserves v CD Centenario | L | 1-2 |
| Panama Liga Prom | 2021/09/10 23:00 | Potros Del Este Reserves v Champions FC Academy | L | 1-3 |
| Panama Liga Prom | 2021/11/06 22:00 | Tauro FC Reserves v Panama City FC | W | 1-2 |
| Panama Liga Prom | 2021/10/31 23:00 | Panama City FC v Plaza Amador Reserves | L | 0-2 |
| Panama Liga Prom | 2021/10/20 21:00 | Alianza FC Reserves v Panama City FC | L | 3-1 |
| Panama Liga Prom | 2021/10/15 23:00 | Sporting San Miguelito Reserves v Panama City FC | L | 1-0 |
| Panama Liga Prom | 2021/10/03 23:00 | Panama City FC v CD Arabe Unido Reserves | L | 0-2 |
| Panama Liga Prom | 2021/09/25 21:00 | Colon C-3 v Panama City FC | L | 2-0 |
| Panama Liga Prom | 2021/09/19 21:00 | Champions FC Academy v Panama City FC | L | 1-0 |
| Panama Liga Prom | 2021/09/13 00:30 | Panama City FC v UMECIT | W | 2-1 |