[3] Birkirkara 2-3 St Lucia [11] 2022-02-27 13:00
Stadium: Ta' Qali National Stadium Round: 20
Home Manager: Andre Paus Away Manager: Oliver Spiteri
Head to Head
| Malta Premier League | 2021/11/21 10:30 | Santa Lucia FC v Birkirkara | L | 2-0 |
| Malta Premier League | 2021/01/10 13:00 | Santa Lucia FC v Birkirkara | D | 0-0 |
| Malta Premier League | 2019/11/09 15:15 | Santa Lucia FC v Birkirkara | W | 0-2 |
| Europe Friendlies | 2018/07/26 16:09 | Birkirkara v Santa Lucia FC | W | 1-0 |
| Malta FA Trophy | 2017/12/02 13:00 | Santa Lucia FC v Birkirkara | W | 0-5 |
Home History
| Malta Premier League | 2022/02/19 15:00 | Hibernians v Birkirkara | W | 2-3 |
| Malta Premier League | 2022/02/13 17:00 | Birkirkara v Sirens | D | 1-1 |
| Malta FA Trophy | 2022/02/10 18:00 | Birkirkara v Fgura United | W | 4-0 |
| Malta Premier League | 2022/02/06 13:00 | Gudja United v Birkirkara | W | 0-1 |
| Malta Premier League | 2022/01/30 17:00 | Birkirkara v Gzira United | W | 1-0 |
| Malta Premier League | 2022/01/26 18:00 | Hamrun Spartans v Birkirkara | D | 0-0 |
| Malta Premier League | 2022/01/23 17:00 | Floriana v Birkirkara | L | 1-0 |
| Malta Premier League | 2022/01/19 20:00 | Birkirkara v Balzan FC | W | 3-2 |
Away History
| Malta Premier League | 2022/02/20 13:00 | Santa Lucia FC v Valletta | W | 2-1 |
| Malta Premier League | 2022/02/13 15:00 | Sliema Wanderers v Santa Lucia FC | D | 1-1 |
| Malta FA Trophy | 2022/02/10 18:00 | Santa Lucia FC v Sirens | W | 4-1 |
| Malta Premier League | 2022/02/05 13:00 | Mosta FC v Santa Lucia FC | L | 1-0 |
| Malta Premier League | 2022/01/29 13:00 | Santa Lucia FC v Hibernians | D | 0-0 |
| Malta Premier League | 2022/01/23 15:00 | Sirens v Santa Lucia FC | L | 2-1 |
| Malta Premier League | 2022/01/19 16:00 | Santa Lucia FC v Gudja United | L | 0-3 |
| Malta Premier League | 2021/12/18 13:00 | Gzira United v Santa Lucia FC | D | 2-2 |