[13] Leyton Orient 2-0 Grimsby [10] 2022-07-30 14:00
Stadium: Matchroom Stadium Round: 1
Referee: Christopher Pollard Home Manager: Richie Wellens Away Manager: Paul Hurst
Head to Head
| England League 2 | 2021/03/02 19:00 | Grimsby v Leyton Orient | W | 0-1 |
| England League 2 | 2020/10/17 16:30 | Leyton Orient v Grimsby | L | 2-3 |
| England League 2 | 2020/01/11 15:00 | Leyton Orient v Grimsby | D | 1-1 |
| England League 2 | 2019/10/19 14:00 | Grimsby v Leyton Orient | W | 0-4 |
| England League 2 | 2017/03/11 15:00 | Leyton Orient v Grimsby | L | 0-3 |
| England League 2 | 2016/08/20 14:00 | Grimsby v Leyton Orient | W | 1-2 |
Home History
| Europe Friendlies | 2022/07/23 14:00 | Dag & Red v Leyton Orient | D | 2-2 |
| Club Friendly List | 2022/07/19 18:00 | Leyton Orient v Portsmouth | L | 2-5 |
| UK Friendlies | 2022/07/12 18:45 | Maidstone Utd v Leyton Orient | D | 0-0 |
| Club Friendly List | 2022/07/08 10:00 | Leyton Orient v Peterborough | L | 0-3 |
| Club Friendly List | 2022/07/04 17:30 | Leyton Orient v West Brom | L | 1-2 |
| Club Friendly List | 2022/07/01 18:00 | Haringey Borough v Leyton Orient | W | 1-2 |
| England League 2 | 2022/05/07 14:00 | Leyton Orient v Tranmere | L | 0-1 |
| England League 2 | 2022/04/30 14:00 | Crawley Town v Leyton Orient | W | 0-2 |
Away History
| Club Friendly List | 2022/07/19 18:15 | Grimsby v Lincoln City | D | 0-0 |
| UK Friendlies | 2022/07/16 14:00 | Alfreton Town v Grimsby | W | 0-4 |
| England National League | 2022/06/05 14:00 | Grimsby v Solihull Moors | W | 2-1 |
| England National League | 2022/05/28 11:30 | Wrexham v Grimsby | W | 4-5 |
| England National League | 2022/05/23 18:45 | Notts County v Grimsby | W | 1-2 |
| England National League | 2022/05/15 14:00 | Eastleigh v Grimsby | D | 4-4 |
| England National League | 2022/05/10 18:45 | Grimsby v Boreham Wood | W | 1-0 |
| England National League | 2022/05/07 14:00 | Grimsby v Maidenhead Utd | L | 1-3 |