Stadium: Leckonby Stadium Round: 1
| NCAAF | 2021/11/13 17:00 | Buffalo State Bengals v St Lawrence Saints | W | 6-41 |
| NCAAF | 2019/11/16 17:00 | Buffalo State Bengals v St Lawrence Saints | W | 26-31 |
| NCAAF | 2022/11/05 16:00 | Rpi Engineers v St Lawrence Saints | L | 10-6 |
| NCAAF | 2022/10/29 16:00 | Rochester Yellowjackets v St Lawrence Saints | W | 31-35 |
| NCAAF | 2022/10/22 17:00 | St Lawrence Saints v Hobart Statesmen | L | 10-31 |
| NCAAF | 2022/10/15 17:00 | Ithaca Bombers v St Lawrence Saints | L | 40-0 |
| NCAAF | 2022/10/08 17:00 | St Lawrence Saints v Union Dutchmen | L | 7-44 |
| NCAAF | 2022/09/24 16:00 | Castleton Spartans v St Lawrence Saints | W | 6-34 |
| NCAAF | 2022/09/16 23:00 | St Lawrence Saints v Morrisville State Mustangs | L | 15-17 |
| NCAAF | 2022/09/10 16:00 | Norwich Cadets v St Lawrence Saints | W | 19-30 |
| NCAAF | 2022/11/05 17:00 | Buffalo State Bengals v Hobart Statesmen | L | 7-63 |
| NCAAF | 2022/10/29 16:00 | Brockport Golden Eagles v Buffalo State Bengals | L | 54-2 |
| NCAAF | 2022/10/21 23:00 | Buffalo State Bengals v Ithaca Bombers | L | 10-51 |
| NCAAF | 2022/10/15 16:00 | Rochester Yellowjackets v Buffalo State Bengals | L | 12-6 |
| NCAAF | 2022/10/08 16:00 | Buffalo State Bengals v Rpi Engineers | L | 14-42 |
| NCAAF | 2022/10/01 17:00 | Union Dutchmen v Buffalo State Bengals | L | 45-0 |
| NCAAF | 2022/09/24 21:00 | Buffalo State Bengals v Morrisville State Mustangs | L | 10-31 |
| NCAAF | 2022/09/17 16:00 | Buffalo State Bengals v Cortland Red Dragons | L | 7-66 |