Stadium: Eddie G. Robinson Memorial Stadium Round: 1
Home Manager: Hue Jackson Away Manager: Clarence McKinney
| NCAAF | 2022/11/13 00:00 | Grambling State v Texas Southern Tigers | W | 7-41 |
| NCAAF | 2021/10/16 19:00 | Texas Southern Tigers v Grambling State | L | 20-34 |
| NCAAF | 2019/11/02 19:00 | Texas Southern Tigers v Grambling State | L | 20-55 |
| NCAAF | 2018/10/13 23:00 | Grambling State v Texas Southern Tigers | L | 34-21 |
| NCAAF | 2017/10/28 19:00 | Grambling State v Texas Southern Tigers | L | 50-24 |
| NCAAF | 2023/09/16 23:00 | Texas Southern Tigers v Rice | L | 7-59 |
| NCAAF | 2023/09/09 19:30 | Texas Southern Tigers v Toledo | L | 3-71 |
| NCAAF | 2023/09/03 00:00 | Prairie View v Texas Southern Tigers | L | 37-34 |
| NCAAF | 2022/11/19 19:00 | Texas Southern Tigers v Alabama | L | 20-24 |
| NCAAF | 2022/11/13 00:00 | Grambling State v Texas Southern Tigers | W | 7-41 |
| NCAAF | 2022/11/05 23:00 | Jackson State v Texas Southern Tigers | L | 41-14 |
| NCAAF | 2022/10/29 19:00 | Texas Southern Tigers v Lincoln Oaklanders | W | 37-2 |
| NCAAF | 2022/10/22 19:00 | Texas Southern Tigers v Alcorn State | W | 34-27 |
| NCAAF | 2023/09/16 19:00 | Grambling State v Florida Memorial University Lions | W | 58-22 |
| NCAAF | 2023/09/09 23:30 | Grambling State v LSU | L | 10-72 |
| NCAAF | 2023/09/02 19:00 | Grambling State v Hampton | L | 31-35 |
| NCAAF | 2022/11/26 19:00 | Grambling State v Southern | L | 17-34 |
| NCAAF | 2022/11/13 00:00 | Grambling State v Texas Southern Tigers | L | 7-41 |
| NCAAF | 2022/11/05 19:00 | Arkansas Pine Bluff v Grambling State | W | 10-36 |
| NCAAF | 2022/10/29 19:00 | Alcorn State v Grambling State | W | 6-35 |
| NCAAF | 2022/10/15 18:00 | Florida A&M v Grambling State | L | 20-16 |