[16] Once Caldas 3-1 Envigado FC [14] 2021-02-06 20:15
Stadium: Estadio Palogrande Round: 5
Referee: Lisandro Enrique Castillo Forero Home Manager: Eduardo Lara Lozano Away Manager: Jose Arastey Eres
Head to Head
| Colombia Cup | 2020/10/29 00:40 | Once Caldas v Envigado FC | W | 2-0 |
| Colombia Cup | 2020/10/22 01:00 | Envigado FC v Once Caldas | L | 3-0 |
| Colombia Primera A | 2020/02/04 23:00 | Envigado FC v Once Caldas | W | 0-1 |
| Colombia Primera A | 2019/10/01 20:30 | Envigado FC v Once Caldas | W | 1-3 |
| Colombia Primera A | 2019/04/09 01:00 | Once Caldas v Envigado FC | W | 1-0 |
| Colombia Primera A | 2018/08/12 22:30 | Once Caldas v Envigado FC | W | 3-1 |
| Colombia Primera A | 2018/02/18 19:00 | Envigado FC v Once Caldas | L | 1-0 |
| Colombia Primera A | 2017/10/29 00:00 | Once Caldas v Envigado FC | D | 1-1 |
| Colombia Primera A | 2017/05/10 00:45 | Envigado FC v Once Caldas | D | 0-0 |
| Colombia Cup | 2017/04/26 21:00 | Envigado FC v Once Caldas | W | 0-1 |
| Colombia Cup | 2017/04/11 21:00 | Once Caldas v Envigado FC | W | 4-2 |
| Colombia Primera A | 2016/09/25 00:45 | Once Caldas v Envigado FC | W | 2-0 |
| Colombia Primera A | 2016/04/23 00:45 | Envigado FC v Once Caldas | W | 0-1 |
| Colombia Cup | 2016/03/17 00:30 | Once Caldas v Envigado FC | L | 0-1 |
| Colombia Cup | 2016/03/10 00:00 | Envigado FC v Once Caldas | L | 1-0 |
| Colombia Primera A | 2015/09/26 19:00 | Once Caldas v Envigado FC | D | 1-1 |
| Colombia Primera A | 2015/04/09 23:00 | Envigado FC v Once Caldas | L | 2-1 |
| Colombia Primera A | 2014/09/07 01:00 | Once Caldas v Envigado FC | W | 2-1 |