[15] Mazatlan FC 2-1 Club America [13] 2022-02-17 01:00
Stadium: Estadio de Mazatlan Round: 2
Referee: Jorge Antonio Perez Duran Home Manager: Benat San Jose Away Manager: Santiago Hernan Solari Poggio
Head to Head
| Mexico Liga MX | 2021/09/12 02:00 | Club America v Mazatlan FC | L | 2-0 |
| Mexico Liga MX | 2021/03/20 03:00 | Mazatlan FC v Club America | L | 0-1 |
| Mexico Liga MX | 2020/09/03 01:00 | Club America v Mazatlan FC | L | 3-1 |
| Europe Friendlies | 2018/07/08 23:30 | Mazatlan FC v Club America | L | 1-2 |
| Mexico Liga MX | 2016/08/14 02:00 | Club America v Mazatlan FC | D | 1-1 |
| Mexico Liga MX | 2016/03/05 23:00 | Club America v Mazatlan FC | L | 4-1 |
| Mexico Liga MX | 2015/09/20 01:30 | Mazatlan FC v Club America | L | 0-3 |
| Mexico Liga MX | 2015/02/07 01:30 | Mazatlan FC v Club America | D | 2-2 |
| Mexico Liga MX | 2014/08/16 22:00 | Club America v Mazatlan FC | L | 3-2 |