[31] Iowa State 10-7 Iowa [4] 2022-09-10 20:00
Stadium: Kinnick Stadium Round: 1
Home Manager: Kirk Ferentz Away Manager: Matt Campbell
Head to Head
| NCAAF | 2021/09/11 20:30 | Iowa v Iowa State | L | 27-17 |
| NCAAF | 2019/09/14 20:00 | Iowa v Iowa State | L | 18-17 |
| NCAAF | 2018/09/08 21:00 | Iowa State v Iowa | L | 3-13 |
| NCAAF | 2017/09/09 16:00 | Iowa v Iowa State | L | 44-41 |
| NCAAF | 2016/09/10 23:30 | Iowa v Iowa State | L | 42-3 |
| NCAAF | 2015/09/12 20:45 | Iowa State v Iowa | L | 17-31 |
| NCAAF | 2014/09/13 19:30 | Iowa v Iowa State | W | 17-20 |
| NCAAF | 2012/09/08 12:00 | Iowa v Iowa State | W | 6-9 |
| NCAAF | 2011/09/10 12:00 | Iowa State v Iowa | W | 44-41 |
| NCAAF | 2010/09/11 12:00 | Iowa v Iowa State | L | 35-7 |
| NCAAF | 2009/09/12 12:00 | Iowa State v Iowa | L | 3-35 |
| NCAAF | 2008/09/13 12:00 | Iowa v Iowa State | L | 17-5 |
| NCAAF | 2007/09/15 12:00 | Iowa State v Iowa | W | 15-13 |
| NCAAF | 2006/09/16 12:00 | Iowa v Iowa State | L | 27-17 |
| NCAAF | 2005/09/10 12:00 | Iowa State v Iowa | W | 23-3 |
| NCAAF | 2004/09/11 12:00 | Iowa v Iowa State | L | 17-10 |
| NCAAF | 2003/09/13 12:00 | Iowa State v Iowa | L | 21-40 |
| NCAAF | 2002/09/14 12:00 | Iowa v Iowa State | W | 31-36 |
| NCAAF | 2001/11/24 12:00 | Iowa State v Iowa | W | 17-14 |
| NCAAF | 2000/09/16 12:00 | Iowa v Iowa State | W | 14-24 |