| Date | R | Home v Away | - | |
|---|---|---|---|---|
| 06/19 09:45 | - | Hume City U21 v Melbourne Knights U21 | W | 0-1 |
| 05/23 03:00 | - | Melbourne Knights U21 v Eastern Lions U21 | D | 1-1 |
| 05/14 08:15 | - | Bentleigh Greens U21 v Melbourne Knights U21 | L | 4-1 |
| 05/09 03:14 | - | Melbourne Knights U21 v South Melbourne U21 | D | 1-1 |
| 05/02 03:00 | - | Melbourne Knights U21 v Dandenong City U21 | W | 3-2 |
| 04/24 05:00 | - | Green Gully U21 v Melbourne Knights U21 | W | 1-9 |
| 04/18 03:00 | - | Melbourne Knights U21 v Altona Magic U21 | D | 1-1 |
| 04/09 08:15 | - | Oakleigh Cannons U21 v Melbourne Knights U21 | L | 3-1 |
| 04/03 04:00 | - | Melbourne Knights U21 v Heidelberg Utd U21 | W | 1-0 |
| 03/27 01:30 | - | Avondale U21 v Melbourne Knights U21 | L | 3-1 |
| 03/21 04:00 | - | Melbourne Knights U21 v Hume City U21 | D | 2-2 |
| 03/14 03:30 | - | St Albans Saints U21 v Melbourne Knights U21 | W | 1-5 |
| 03/07 04:00 | - | Melbourne Knights U21 v Dandenong Thunder U21 | L | 2-4 |
| 02/27 04:00 | - | Port Melbourne U21 v Melbourne Knights U21 | W | 0-4 |