[16] Villa Espanola 1-3 Penarol [1] 2021-10-23 22:00
Stadium: Estadio Obdulio Varela Round: 8
Referee: Antonio Garcia Home Manager: Julio Mozzo Away Manager: Mauricio Larriera
Head to Head
| Uruguay Apertura | 2021/06/26 21:00 | Penarol v Villa Espanola | D | 1-1 |
| Uruguay Apertura | 2016/10/15 22:15 | Penarol v Villa Espanola | L | 2-1 |